[PDF.63no] An Immunotoxin for the Depletion of Autoreactive B Cells in MS: Design, expression, and characterization of an autoimmunotoxin for the specific depletion of autoreactive B cells in multiple sclerosis

An Immunotoxin for the Depletion of Autoreactive B Cells in MS: Design, expression, and characterization of an autoimmunotoxin for the specific depletion of autoreactive B cells in multiple sclerosis

[PDF.nr59] An Immunotoxin for the Depletion of Autoreactive B Cells in MS: Design, expression, and characterization of an autoimmunotoxin for the specific depletion of autoreactive B cells in multiple sclerosis

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 | #17121736 in Books |  VDM Verlag Dr. Müller |  2010-08-18 | Original language:English | PDF # 1 |  8.66 x.19 x5.91l,.28 | File type: PDF | 80 pages

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||About the Author|Sigrun Klandt, Dipl.-Ing.: Studium des Bioingenieurwesens an der FH Aachen. F&E Executive bei der BSV BioScience GmbH, Baesweiler.

The aim of the presented work was the design, production, and characterisation of a novel immunotoxin in the context of MS. Proteins were expressed in a prokaryotic and eukaryotic system, respectively. Stable producing 293T cell populations were established for the reference protein PLP that showed a good expression yield and a high purity after purification was obtained. This is the first time that a functional PLP fusion protein was expressed in 293T cells and...

You easily download any file type for your device.An Immunotoxin for the Depletion of Autoreactive B Cells in MS: Design, expression, and characterization of an autoimmunotoxin for the specific depletion of autoreactive B cells in multiple sclerosis   |  Sigrun Klandt. A good, fresh read, highly recommended.

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