[PDF.87jn] Growth Factor VN Complexes Accelerate the Healing of Diabetic Ulcers: Vitronectin _ Insulin Growth Factor - Insulin Growth Factor Binding Protein ... and proliferation in skin from diabetics

Growth Factor VN Complexes Accelerate the Healing of Diabetic Ulcers: Vitronectin _ Insulin Growth Factor - Insulin Growth Factor Binding Protein ... and proliferation in skin from diabetics

[PDF.wc48] Growth Factor VN Complexes Accelerate the Healing of Diabetic Ulcers: Vitronectin _ Insulin Growth Factor - Insulin Growth Factor Binding Protein ... and proliferation in skin from diabetics

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 |  VDM Verlag Dr. Müller |  2010-05-07 | Original language:English | PDF # 1 |  8.66 x.56 x5.91l,.81 | File type: PDF | 248 pages

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The findings outlined in this thesis show that VN:IGFBP:IGF-I complexes can elicit enhanced growth and migration in cells derived from skin from both normal and diabetic patients. Further, these responses are maintained in conditions found in the diabetic wound microenvironment, namely in the presence of high glucose and high calcium. Together these findings demonstrate the potential of the VN:IGFBP:IGF complexes as wound healing agents to treat wounds, especially diabet...

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